PGT in IVF Explained: How Genetic Testing Improves IVF Success (2025 Update)

November 4, 2025

🧬 PGT in IVF Explained: How Genetic Testing Improves IVF Success (2025 Update)

A Modern Approach to Choosing the Healthiest Embryos

🌸 Introduction

In the journey of IVF, one of the most common questions we hear is:

“Can genetic testing really improve our chances of a healthy baby?”

The answer is a confident yes — thanks to Preimplantation Genetic Testing (PGT).

PGT allows doctors to analyze embryos before transfer, identifying the ones with the best genetic health — improving pregnancy rates, reducing miscarriage risk, and ensuring the birth of a healthy baby.

“PGT brings precision to IVF — we don’t just create embryos, we select the healthiest ones for success.”
— Dr. Sandeep, Senior Embryologist & IVF Specialist

🧠 What Is PGT (Preimplantation Genetic Testing)?

PGT is an advanced laboratory technique that screens embryos for chromosomal or genetic abnormalities before they are transferred into the uterus during an IVF cycle.

It helps ensure that only genetically normal embryos are used for implantation — increasing the chances of a successful, healthy pregnancy.

Think of PGT as IVF’s quality control — ensuring your future baby’s genetic blueprint starts strong.

🧫 Types of PGT and Their Purpose

Type of PGT Full Form What It Detects Best For
PGT-A Preimplantation Genetic Testing for Aneuploidies Checks for extra/missing chromosomes Women >35 years, recurrent miscarriages
PGT-M Preimplantation Genetic Testing for Monogenic Disorders Detects specific inherited diseases (e.g. Thalassemia, Cystic Fibrosis) Couples with known genetic disorders
PGT-SR Preimplantation Genetic Testing for Structural Rearrangements Detects chromosomal translocations Couples with previous abnormal pregnancies

“Every embryo looks normal under a microscope — PGT reveals what the eye can’t see.”

⚙️ How the PGT Process Works (Step-by-Step)

Step 1: IVF and Embryo Formation

  • Eggs and sperm are combined through IVF or ICSI to create embryos.

Step 2: Embryo Development (Day 5–6)

  • Embryos are cultured to the blastocyst stage (100+ cells).

Step 3: Embryo Biopsy

  • A few cells are carefully removed from the outer layer (trophectoderm) — the embryo itself remains unharmed.

Step 4: Genetic Analysis

  • Biopsied cells are analyzed using Next-Generation Sequencing (NGS) to detect chromosomal or genetic abnormalities.

Step 5: Embryo Freezing (Vitrification)

  • Tested embryos are frozen while results are processed (3–5 days).

Step 6: Transfer of Healthy Embryo

  • Only chromosomally normal embryos are selected for transfer, maximizing success.

“The PGT process is completely safe for embryos — we’ve been performing it with 99% accuracy.”

📊 IVF Success Rates With and Without PGT

Parameter Standard IVF IVF + PGT-A
Implantation Rate 40–50% 65–75%
Clinical Pregnancy Rate 45–55% 70–80%
Miscarriage Rate 20–25% <8%
Healthy Birth Rate 45–55% 75–85%

PGT doesn’t guarantee pregnancy — but it dramatically improves the odds.

🧬 Who Should Consider PGT?

PGT is particularly recommended for:

✅ Women over 35 years (higher chromosomal risk)
✅ Couples with multiple IVF failures
✅ Couples with recurrent miscarriages
✅ Known genetic disorders in family history
✅ Male infertility cases with DNA fragmentation issues
✅ Donor egg/sperm cycles (to ensure genetic safety)

“PGT gives clarity — turning uncertainty into informed decision-making.”

💰 Cost of PGT in India (2025 Estimate)

Service Approx. Cost (USD)
IVF Cycle $2,800 – $4,000
PGT Testing (per batch of embryos) $1,200 – $1,800
Total (IVF + PGT) $4,000 – $5,800

✅ 70% cheaper than USA/UK
✅ Includes genetic counseling and freezing
✅ Performed in certified genetic labs under ART Act compliance

“In India, PGT offers global-grade precision at a fraction of international cost.”

⚖️ Legal & Ethical Regulations (2025 Update)

Under India’s ART Act (2021) and Surrogacy Regulation Act (2021):

  • PGT can only be performed at registered ART laboratories.

  • Genetic testing requires written patient consent.

  • Embryos cannot be modified — only screened.

  • Data privacy and sample tracking are mandatory under ICMR guidelines.

“India’s fertility laws ensure that every PGT procedure is ethical, transparent, and patient-centered.”

💬 Real Patient Story

“After three failed IVF attempts, we opted for PGT . Our doctor found chromosomal issues in previous embryos. With PGT-A, we transferred a healthy one — and now have our baby girl. It changed everything.”
— Rania & Omar, UAE

This story reflects what many couples discover — PGT transforms IVF from chance into choice.

🌿 Advantages of PGT

✅ Higher implantation & success rates
✅ Reduced miscarriage risk
✅ Healthier pregnancies
✅ Identifies genetic diseases early
✅ Saves time and cost in the long term

🩺 Final Thoughts

PGT has revolutionized IVF by adding genetic intelligence to reproductive medicine.
It gives couples clarity, confidence, and control over their fertility journey.

At Zeeva Fertility, our expert embryologists and geneticists perform safe, accurate, and ethical PGT testing for couples from India, the UAE, Africa, and Europe — helping them achieve healthy pregnancies with peace of mind.

“Science doesn’t just create life — it safeguards it.”

📞 Learn If PGT Is Right for You

Schedule a free genetic fertility consultation to see whether PGT can benefit your IVF journey.

🌐 Website: www.fertycure.com
📱 WhatsApp: +91-9044346292
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